Yes, it is. The cat's territory consists of familiar scents that she has left herself by scratching, giving head bumps, sleeping,...
Those familiar scents provide a feeling of security. You remove this sense when the cat goes to a hotel (unless you bring a suitcase with cat stuff, therefore bringing “home” to the hotel!).
If the cat stays at home during your absence, her routine might change as well. Cats are sensitive to this and it can cause stress.
Are you certain that staying at home is the least stressful option for your cat? Then you can contact us for our catsitting service at home: Chat-o-Maison. It's a customized service, with the same professional advice and approach!